Epimagnolin A, a furfuran lignan, shows mild antiplasmodial activities (IC50=5.7 μg/mL) without noticeable toxicity on mammalian normal cells.

Product information

CAS Number: 41689-51-4

Molecular Weight: 416.46

Formula: C23H28O7

Chemical Name: (1S,3aR,4R,6aR)-1-(3,4-dimethoxyphenyl)-1,3a,4,6a-tetrahydrogenio-4-(3,4,5-trimethoxyphenyl)-hexahydrofuro[3,4-c]furan

Smiles: COC1C=C(C=C(OC)C=1OC)[C@@H]1OC[C@@H]2[C@H](OC[C@@H]21)C1=CC(OC)=C(C=C1)OC

InChiKey: MFIHSKBTNZNJIK-FRMGNDQPSA-N

InChi: InChI=1S/C23H28O7/c1-24-17-7-6-13(8-18(17)25-2)21-15-11-30-22(16(15)12-29-21)14-9-19(26-3)23(28-5)20(10-14)27-4/h6-10,15-16,21-22H,11-12H2,1-5H3/t15-,16-,21+,22-/m0/s1

Technical Data

Appearance: Solid Power

Purity: ≥98% (or refer to the Certificate of Analysis)

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis

Storage Condition: Dry, dark and -20 ^oC for 1 year or refer to the Certificate of Analysis.

Shelf Life: ≥12 months if stored properly.

Stock Solution Storage: 0 - 4 ^oC for 1 month or refer to the Certificate of Analysis.

Drug Formulation: To be determined

HS Tariff Code: 382200

References:

1. Ortet R, et, al. Furfuran lignans and a flavone from Artemisia gorgonum Webb and their in vitro activity against Plasmodium falciparum. J Ethnopharmacol. 2011 Nov 18;138(2):637-40.

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