SPOP Polyclonal Antibody

Sizes: 50μL, 100μL

Catalogue Numbers: RA30001-50, RA30001-100

Citations, Manuals and MSDS Available upon request.

Background: speckle type BTB/POZ protein (SPOP) Homo sapiens This gene encodes a protein that may modulate the transcriptional repression activities of death-associated protein 6 (DAXX), which interacts with histone deacetylase, core histones, and other histone-associated proteins. In mouse, the encoded protein binds to the putative leucine zipper domain of macroH2A1.2, a variant H2A histone that is enriched on inactivated X chromosomes. The BTB/POZ domain of this protein has been shown in other proteins to mediate transcriptional repression and to interact with components of histone deacetylase co-repressor complexes. Alternative splicing of this gene results in multiple transcript variants encoding the same protein. [provided by RefSeq, Jul 2008],

Condition: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Storage Instructions: -20°C/1 year

Recommended dilutions: WB 1:500-2000, ELISA 1:10000-20000

Alternative Names: Speckle-type POZ protein (HIB homolog 1) (Roadkill homolog 1)

Applications: WB; ELISA

Species Cross-Reactivity: Human; Mouse; Rat

GeneID (Human): 8405

Protein MW (KDa): 42

SWISS: O43791

Source: Rabbit

Research Use Only