STAT2 Polyclonal Antibody

Sizes: 50μL, 100μL

Catalogue Numbers: RA30104-50, RA30104-100

Citations, Manuals and MSDS Available upon request.

Background: signal transducer and activator of transcription 2 (STAT2) Homo sapiens The protein encoded by this gene is a member of the STAT protein family. In response to cytokines and growth factors, STAT family members are phosphorylated by the receptor associated kinases, and then form homo- or heterodimers that translocate to the cell nucleus where they act as transcription activators. In response to interferon (IFN), this protein forms a complex with STAT1 and IFN regulatory factor family protein p48 (ISGF3G), in which this protein acts as a transactivator, but lacks the ability to bind DNA directly. Transcription adaptor P300/CBP (EP300/CREBBP) has been shown to interact specifically with this protein, which is thought to be involved in the process of blocking IFN-alpha response by adenovirus. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Mar 2010],

Condition: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Storage Instructions: -20°C/1 year

Recommended dilutions: Western Blot: 1/500 - 1/2000.IHC-p:1:50-300. Not yet tested in other applications.

Alternative Names: Signal transducer and activator of transcription 2 (p113)

Applications: WB; IHC-p; IF (paraffin section)

Species Cross-Reactivity: Human; Rat; Mouse

GeneID (Human): 6773

Protein MW (KDa): 98

SWISS: P52630

Source: Rabbit

Research Use Only